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Han-Jie Zhou Selected Research

ATPases Associated with Diverse Cellular Activities

1/2021Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.
11/2017The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma.
11/2015Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis.

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Han-Jie Zhou Research Topics

Disease

6Neoplasms (Cancer)
01/2019 - 05/2009
2Multiple Myeloma
11/2017 - 05/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2021
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021
1Non-Hodgkin Lymphoma (Lymphosarcoma)
05/2009

Drug/Important Bio-Agent (IBA)

3ATPases Associated with Diverse Cellular ActivitiesIBA
01/2021 - 11/2015
2Adenosine Triphosphatases (ATPase)IBA
01/2021 - 01/2019
2CB-5083IBA
11/2017 - 11/2015
2Proteasome Endopeptidase Complex (Proteasome)IBA
11/2017 - 05/2009
1Phosphotransferases (Kinase)IBA
01/2021
1Small Interfering RNA (siRNA)IBA
01/2021
1Valosin Containing ProteinIBA
01/2021
1UbiquitinIBA
11/2017
1Proteasome InhibitorsIBA
11/2017
1Ubiquitinated ProteinsIBA
11/2015
1KinesinsIBA
04/2010
1carfilzomibIBA
05/2009

Therapy/Procedure

2Oral Administration
12/2015 - 05/2009